ChloroquineV1, Main, Exploration, bibRecord, 001A40

SEVERE HYDROXYCHLOROQUINE MYOPATHY

Identifieur interne : 001A40 ( Main/Exploration ); précédent : 001A39; suivant : 001A41

SEVERE HYDROXYCHLOROQUINE MYOPATHY

Auteurs : Hoda Abdel-Hamid [États-Unis] ; Chester V. Oddis [États-Unis] ; David Lacomis [États-Unis]

Source :

Muscle & nerve [ 0148-639X ] ; 2008.

RBID : Pascal:08-0430723

Descripteurs français

Pascal (Inist)
- Pathologie des poumons, Sclérodermie, Myopathie, Pathologie du tissu conjonctif, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Connective tissue disease, Human, Lung disease, Myopathy, Scleroderma.

Abstract

Hydroxychloroquine causes a vacuolar myopathy that is usually of mild to moderate severity. The myopathy may be underrecognized, especially in patients who receive multiple other medications for complex illnesses. We report two patients with connective tissue diseases and unusually severe, histopathologically proven hydroxychloroquine myopathy. Both had ventilatory failure; one also had primary pulmonary disease associated with scleroderma, but the other lacked a pulmonary etiology. The ventilatory failure and subsequent medical complications led to death despite discontinuation of hydroxychloroquine, thereby underscoring the potential severity of hydroxychloroquine myopathy and the need for its early recognition.

Affiliations:

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to stream PascalFrancis, to step Curation: 000036
to stream PascalFrancis, to step Checkpoint: 000030
to stream Main, to step Merge: 001A49
to stream Main, to step Curation: 001A40

Le document en format XML

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<term>Sclérodermie</term>
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<term>Pathologie du  tissu conjonctif</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Hydroxychloroquine causes a vacuolar myopathy that is usually of mild to moderate severity. The myopathy may be underrecognized, especially in patients who receive multiple other medications for complex illnesses. We report two patients with connective tissue diseases and unusually severe, histopathologically proven hydroxychloroquine myopathy. Both had ventilatory failure; one also had primary pulmonary disease associated with scleroderma, but the other lacked a pulmonary etiology. The ventilatory failure and subsequent medical complications led to death despite discontinuation of hydroxychloroquine, thereby underscoring the potential severity of hydroxychloroquine myopathy and the need for its early recognition.</div>
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SEVERE HYDROXYCHLOROQUINE MYOPATHY

SEVERE HYDROXYCHLOROQUINE MYOPATHY

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri